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Cryo-EM demonstrates the in vitro proliferation of an ex vivo amyloid fibril morphology by seeding
Several studies showed that seeding of solutions of monomeric fibril proteins with ex vivo amyloid fibrils accelerated the kinetics of fibril formation in vitro but did not necessarily replicate the seed structure. In this research we use cryo-electron microscopy and other methods to analyze the abi...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748726/ https://www.ncbi.nlm.nih.gov/pubmed/35013242 http://dx.doi.org/10.1038/s41467-021-27688-5 |