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Thermodynamic surprises of Cu(II)–amylin analogue complexes in membrane mimicking solutions

Membrane environment often has an important effect on the structure, and therefore also on the coordination mode of biologically relevant metal ions. This is also true in the case of Cu(II) coordination to amylin analogues—rat amylin, amylin(1–19), pramlintide and Ac-pramlintide, which offer N-termi...

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Detalles Bibliográficos
Autores principales: Dzień, Emilia, Dudek, Dorota, Witkowska, Danuta, Rowińska-Żyrek, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748748/
https://www.ncbi.nlm.nih.gov/pubmed/35013439
http://dx.doi.org/10.1038/s41598-021-04197-5