Metformin prevents methylglyoxal-induced apoptosis by suppressing oxidative stress in vitro and in vivo

Methylglyoxal (MGO) is an active metabolite of glucose and plays a prominent role in the pathogenesis of diabetic vascular complications, including endothelial cell apoptosis induced by oxidative stress. Metformin (MET), a widely prescribed antidiabetic agent, appears to reduce excessive reactive ox...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Wang, Yanan, Yang, Qinzhi, Xu, Chunrong, Zheng, Youkun, Wang, Liqun, Wu, Jianbo, Zeng, Min, Luo, Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748764/
https://www.ncbi.nlm.nih.gov/pubmed/35013107
http://dx.doi.org/10.1038/s41419-021-04478-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748764/
https://www.ncbi.nlm.nih.gov/pubmed/35013107
http://dx.doi.org/10.1038/s41419-021-04478-x

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