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Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry

Single-cell proteomics can reveal cellular phenotypic heterogeneity and cell-specific functional networks underlying biological processes. Here, we present a streamlined workflow combining microfluidic chips for all-in-one proteomic sample preparation and data-independent acquisition (DIA) mass spec...

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Detalles Bibliográficos
Autores principales: Gebreyesus, Sofani Tafesse, Siyal, Asad Ali, Kitata, Reta Birhanu, Chen, Eric Sheng-Wen, Enkhbayar, Bayarmaa, Angata, Takashi, Lin, Kuo-I, Chen, Yu-Ju, Tu, Hsiung-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748772/
https://www.ncbi.nlm.nih.gov/pubmed/35013269
http://dx.doi.org/10.1038/s41467-021-27778-4