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Maternal regulation of biliary disease in neonates via gut microbial metabolites

Maternal seeding of the microbiome in neonates promotes a long-lasting biological footprint, but how it impacts disease susceptibility in early life remains unknown. We hypothesized that feeding butyrate to pregnant mice influences the newborn’s susceptibility to biliary atresia, a severe cholangiop...

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Detalles Bibliográficos
Autores principales: Jee, Jai Junbae, Yang, Li, Shivakumar, Pranavkumar, Xu, Pei-pei, Mourya, Reena, Thanekar, Unmesha, Yu, Pu, Zhu, Yu, Pan, Yongkang, Wang, Haibin, Duan, Xufei, Ye, Yongqin, Wang, Bin, Jin, Zhu, Liu, Yuanmei, Cao, Zhiqing, Watanabe-Chailland, Miki, Romick-Rosendale, Lindsey E., Wagner, Michael, Fei, Lin, Luo, Zhenhua, Ollberding, Nicholas J., Tang, Shao-tao, Bezerra, Jorge A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748778/
https://www.ncbi.nlm.nih.gov/pubmed/35013245
http://dx.doi.org/10.1038/s41467-021-27689-4