GPR182 limits antitumor immunity via chemokine scavenging in mouse melanoma models

For many solid tumors, immune checkpoint blockade therapy has become first line treatment, yet a large proportion of patients with immunologically cold tumors do not benefit due to the paucity of tumor infiltrating lymphocytes. Here we show that the orphan G Protein-Coupled Receptor 182 (GPR182) con...

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Detalles Bibliográficos
Autores principales: Torphy, Robert J., Sun, Yi, Lin, Ronggui, Caffrey-Carr, Alayna, Fujiwara, Yuki, Ho, Felix, Miller, Emily N., McCarter, Martin D., Lyons, Traci R., Schulick, Richard D., Kedl, Ross M., Zhu, Yuwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748779/
https://www.ncbi.nlm.nih.gov/pubmed/35013216
http://dx.doi.org/10.1038/s41467-021-27658-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748779/
https://www.ncbi.nlm.nih.gov/pubmed/35013216
http://dx.doi.org/10.1038/s41467-021-27658-x

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