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Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT

FACT is a histone chaperone that participates in nucleosome removal and reassembly during transcription and replication. We used electron microscopy to study FACT, FACT:Nhp6 and FACT:Nhp6:nucleosome complexes, and found that all complexes adopt broad ranges of configurations, indicating high flexibi...

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Detalles Bibliográficos
Autores principales: Sivkina, Anastasiia L., Karlova, Maria G., Valieva, Maria E., McCullough, Laura L., Formosa, Timothy, Shaytan, Alexey K., Feofanov, Alexey V., Kirpichnikov, Mikhail P., Sokolova, Olga S., Studitsky, Vasily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748794/
https://www.ncbi.nlm.nih.gov/pubmed/35013515
http://dx.doi.org/10.1038/s42003-021-02948-8