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G-quadruplex DNA structures in human stem cells and differentiation

The establishment of cell identity during embryonic development involves the activation of specific gene expression programmes and is underpinned by epigenetic factors including DNA methylation and histone post-translational modifications. G-quadruplexes are four-stranded DNA secondary structures (G...

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Detalles Bibliográficos
Autores principales: Zyner, Katherine G., Simeone, Angela, Flynn, Sean M., Doyle, Colm, Marsico, Giovanni, Adhikari, Santosh, Portella, Guillem, Tannahill, David, Balasubramanian, Shankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748810/
https://www.ncbi.nlm.nih.gov/pubmed/35013231
http://dx.doi.org/10.1038/s41467-021-27719-1