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GPR120 prevents colorectal adenocarcinoma progression by sustaining the mucosal barrier integrity

GPR120 (encoded by FFAR4 gene) is a receptor for long chain fatty acids, activated by ω-3 Polyunsaturated Fatty Acids (PUFAs), and expressed in many cell types. Its role in the context of colorectal cancer (CRC) is still puzzling with many controversial evidences. Here, we explored the involvement o...

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Detalles Bibliográficos
Autores principales: Rubbino, Federica, Garlatti, Valentina, Garzarelli, Valeria, Massimino, Luca, Spanò, Salvatore, Iadarola, Paolo, Cagnone, Maddalena, Giera, Martin, Heijink, Marieke, Guglielmetti, Simone, Arena, Vincenzo, Malesci, Alberto, Laghi, Luigi, Danese, Silvio, Vetrano, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748819/
https://www.ncbi.nlm.nih.gov/pubmed/35013389
http://dx.doi.org/10.1038/s41598-021-03787-7