TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV

The Human Silencing Hub (HUSH) complex constituted of TASOR, MPP8 and Periphilin recruits the histone methyl-transferase SETDB1 to spread H3K9me3 repressive marks across genes and transgenes in an integration site-dependent manner. The deposition of these repressive marks leads to heterochromatin fo...

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Detalles Bibliográficos
Autores principales: Matkovic, Roy, Morel, Marina, Lanciano, Sophie, Larrous, Pauline, Martin, Benjamin, Bejjani, Fabienne, Vauthier, Virginie, Hansen, Maike M. K., Emiliani, Stéphane, Cristofari, Gael, Gallois-Montbrun, Sarah, Margottin-Goguet, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748822/
https://www.ncbi.nlm.nih.gov/pubmed/35013187
http://dx.doi.org/10.1038/s41467-021-27650-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748822/
https://www.ncbi.nlm.nih.gov/pubmed/35013187
http://dx.doi.org/10.1038/s41467-021-27650-5

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