Cargando…

Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution

Shuttling of macromolecules between nucleus and cytoplasm is a tightly regulated process mediated through specific interactions between cargo and nuclear transport proteins. In the classical nuclear import pathway, importin alpha recognizes cargo exhibiting a nuclear localization signal, and this co...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsimbalyuk, S., Donnelly, C. M., Forwood, J. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748863/
https://www.ncbi.nlm.nih.gov/pubmed/35013395
http://dx.doi.org/10.1038/s41598-021-03729-3