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Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution
Shuttling of macromolecules between nucleus and cytoplasm is a tightly regulated process mediated through specific interactions between cargo and nuclear transport proteins. In the classical nuclear import pathway, importin alpha recognizes cargo exhibiting a nuclear localization signal, and this co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748863/ https://www.ncbi.nlm.nih.gov/pubmed/35013395 http://dx.doi.org/10.1038/s41598-021-03729-3 |