Crystal structure and functional implication of bacterial STING

Mammalian innate immune sensor STING (STimulator of INterferon Gene) was recently found to originate from bacteria. During phage infection, bacterial STING sense c-di-GMP generated by the CD-NTase (cGAS/DncV-like nucleotidyltransferase) encoded in the same operon and signal suicide commitment as a d...

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Detalles Bibliográficos
Autores principales: Ko, Tzu-Ping, Wang, Yu-Chuan, Yang, Chia-Shin, Hou, Mei-Hui, Chen, Chao-Jung, Chiu, Yi-Fang, Chen, Yeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748872/
https://www.ncbi.nlm.nih.gov/pubmed/35013136
http://dx.doi.org/10.1038/s41467-021-26583-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748872/
https://www.ncbi.nlm.nih.gov/pubmed/35013136
http://dx.doi.org/10.1038/s41467-021-26583-3

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