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Crystal structure and functional implication of bacterial STING

Mammalian innate immune sensor STING (STimulator of INterferon Gene) was recently found to originate from bacteria. During phage infection, bacterial STING sense c-di-GMP generated by the CD-NTase (cGAS/DncV-like nucleotidyltransferase) encoded in the same operon and signal suicide commitment as a d...

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Detalles Bibliográficos
Autores principales:	Ko, Tzu-Ping, Wang, Yu-Chuan, Yang, Chia-Shin, Hou, Mei-Hui, Chen, Chao-Jung, Chiu, Yi-Fang, Chen, Yeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748872/ https://www.ncbi.nlm.nih.gov/pubmed/35013136 http://dx.doi.org/10.1038/s41467-021-26583-3

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