Structures of the human peroxisomal fatty acid transporter ABCD1 in a lipid environment

The peroxisomal very long chain fatty acid (VLCFA) transporter ABCD1 is central to fatty acid catabolism and lipid biosynthesis. Its dysfunction underlies toxic cytosolic accumulation of VLCFAs, progressive demyelination, and neurological impairments including X-linked adrenoleukodystrophy (X-ALD)....

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Detalles Bibliográficos
Autores principales: Le, Le Thi My, Thompson, James Robert, Dang, Phuoc Xuan, Bhandari, Janarjan, Alam, Amer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748874/
https://www.ncbi.nlm.nih.gov/pubmed/35013584
http://dx.doi.org/10.1038/s42003-021-02970-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748874/
https://www.ncbi.nlm.nih.gov/pubmed/35013584
http://dx.doi.org/10.1038/s42003-021-02970-w

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