Proximity labeling identifies a repertoire of site-specific R-loop modulators

R-loops are three-stranded nucleic acid structures that accumulate on chromatin in neurological diseases and cancers and contribute to genome instability. Using a proximity-dependent labeling system, we identified distinct classes of proteins that regulate R-loops in vivo through different mechanism...

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Detalles Bibliográficos
Autores principales: Yan, Qingqing, Wulfridge, Phillip, Doherty, John, Fernandez-Luna, Jose L., Real, Pedro J., Tang, Hsin-Yao, Sarma, Kavitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748879/
https://www.ncbi.nlm.nih.gov/pubmed/35013239
http://dx.doi.org/10.1038/s41467-021-27722-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748879/
https://www.ncbi.nlm.nih.gov/pubmed/35013239
http://dx.doi.org/10.1038/s41467-021-27722-6

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