Carbene-catalyzed atroposelective synthesis of axially chiral styrenes

Axially chiral styrenes bearing a chiral axis between a sterically non-congested acyclic alkene and an aryl ring are difficult to prepare due to low rotational barrier of the axis. Disclosed here is an N-heterocyclic carbene (NHC) catalytic asymmetric solution to this problem. Our reaction involves...

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Detalles Bibliográficos
Autores principales: Yan, Jia-Lei, Maiti, Rakesh, Ren, Shi-Chao, Tian, Weiyi, Li, Tingting, Xu, Jun, Mondal, Bivas, Jin, Zhichao, Chi, Yonggui Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748895/
https://www.ncbi.nlm.nih.gov/pubmed/35013298
http://dx.doi.org/10.1038/s41467-021-27771-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748895/
https://www.ncbi.nlm.nih.gov/pubmed/35013298
http://dx.doi.org/10.1038/s41467-021-27771-x

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