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GFAP splice variants fine-tune glioma cell invasion and tumour dynamics by modulating migration persistence

Glioma is the most common form of malignant primary brain tumours in adults. Their highly invasive nature makes the disease incurable to date, emphasizing the importance of better understanding the mechanisms driving glioma invasion. Glial fibrillary acidic protein (GFAP) is an intermediate filament...

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Detalles Bibliográficos
Autores principales: Uceda-Castro, Rebeca, van Asperen, Jessy V., Vennin, Claire, Sluijs, Jacqueline A., van Bodegraven, Emma J., Margarido, Andreia S., Robe, Pierre A. J., van Rheenen, Jacco, Hol, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748899/
https://www.ncbi.nlm.nih.gov/pubmed/35013418
http://dx.doi.org/10.1038/s41598-021-04127-5