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Protein interaction networks define the genetic architecture of preterm birth

The likely genetic architecture of complex diseases is that subgroups of patients share variants in genes in specific networks sufficient to express a shared phenotype. We combined high throughput sequencing with advanced bioinformatic approaches to identify such subgroups of patients with variants...

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Detalles Bibliográficos
Autores principales: Uzun, Alper, Schuster, Jessica S., Stabila, Joan, Zarate, Valeria, Tollefson, George A., Agudelo, Anthony, Kothiyal, Prachi, Wong, Wendy S. W., Padbury, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748950/
https://www.ncbi.nlm.nih.gov/pubmed/35013336
http://dx.doi.org/10.1038/s41598-021-03427-0