JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton

Lysosome axonal transport is important for the clearance of cargoes sequestered by the endocytic and autophagic pathways. Building on observations that mutations in the JIP3 (MAPK8IP3) gene result in lysosome-filled axonal swellings, we analyzed the impact of JIP3 depletion on the cytoskeleton of hu...

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Detalles Bibliográficos
Autores principales: Rafiq, N. M., Lyons, L. L., Gowrishankar, S., De Camilli, P., Ferguson, S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748971/
https://www.ncbi.nlm.nih.gov/pubmed/35013510
http://dx.doi.org/10.1038/s42003-021-02945-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748971/
https://www.ncbi.nlm.nih.gov/pubmed/35013510
http://dx.doi.org/10.1038/s42003-021-02945-x

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