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JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton
Lysosome axonal transport is important for the clearance of cargoes sequestered by the endocytic and autophagic pathways. Building on observations that mutations in the JIP3 (MAPK8IP3) gene result in lysosome-filled axonal swellings, we analyzed the impact of JIP3 depletion on the cytoskeleton of hu...
Autores principales: | Rafiq, N. M., Lyons, L. L., Gowrishankar, S., De Camilli, P., Ferguson, S. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748971/ https://www.ncbi.nlm.nih.gov/pubmed/35013510 http://dx.doi.org/10.1038/s42003-021-02945-x |
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