CCND3 is indispensable for the maintenance of B-cell acute lymphoblastic leukemia

The D-type cyclins (CCND1, CCND2, and CCND3) in association with CDK4/6 are known drivers of cell cycle progression. We reported previously that inactivation of FOXO1 confers growth arrest and apoptosis in B-ALL, partially mediated by subsequent depletion of CCND3. Given that previously the canonica...

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Detalles Bibliográficos
Autores principales: Ketzer, Franz, Abdelrasoul, Hend, Vogel, Mona, Marienfeld, Ralf, Müschen, Markus, Jumaa, Hassan, Wirth, Thomas, Ushmorov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748974/
https://www.ncbi.nlm.nih.gov/pubmed/35013097
http://dx.doi.org/10.1038/s41389-021-00377-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748974/
https://www.ncbi.nlm.nih.gov/pubmed/35013097
http://dx.doi.org/10.1038/s41389-021-00377-0

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