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Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage

Aged microglia display augmented inflammatory activity after neural injury. Although aging is a risk factor for poor outcome after brain insults, the precise impact of aging-related alterations in microglia on neural injury remains poorly understood. Microglia can be eliminated via pharmacological i...

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Detalles Bibliográficos
Autores principales: Li, Xiuping, Gao, Xiaolin, Zhang, Wenyan, Liu, Mingming, Han, Zhaoli, Li, Minshu, Lei, Ping, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748975/
https://www.ncbi.nlm.nih.gov/pubmed/35013119
http://dx.doi.org/10.1038/s41419-021-04424-x