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Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage
Aged microglia display augmented inflammatory activity after neural injury. Although aging is a risk factor for poor outcome after brain insults, the precise impact of aging-related alterations in microglia on neural injury remains poorly understood. Microglia can be eliminated via pharmacological i...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748975/ https://www.ncbi.nlm.nih.gov/pubmed/35013119 http://dx.doi.org/10.1038/s41419-021-04424-x |