Cargando…

Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage

Aged microglia display augmented inflammatory activity after neural injury. Although aging is a risk factor for poor outcome after brain insults, the precise impact of aging-related alterations in microglia on neural injury remains poorly understood. Microglia can be eliminated via pharmacological i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiuping, Gao, Xiaolin, Zhang, Wenyan, Liu, Mingming, Han, Zhaoli, Li, Minshu, Lei, Ping, Liu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748975/ https://www.ncbi.nlm.nih.gov/pubmed/35013119 http://dx.doi.org/10.1038/s41419-021-04424-x

Ejemplares similares

Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation
por: Guo, Mengtian, et al.
Publicado: (2023)

Dyslipidemic Diet Induces Mobilization of Peripheral Neutrophils and Monocytes That Exacerbate Hemorrhagic Brain Injury and Neuroinflammation
por: Li, Xiuping, et al.
Publicado: (2020)

A TSPO ligand attenuates brain injury after intracerebral hemorrhage
por: Li, Minshu, et al.
Publicado: (2017)

Induced neural stem cells suppressed neuroinflammation by inhibiting the microglial pyroptotic pathway in intracerebral hemorrhage rats
por: Liu, Jiaxin, et al.
Publicado: (2023)

Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway
por: Lei, Pan, et al.
Publicado: (2023)

Astrocytic Sonic Hedgehog Alleviates Intracerebral Hemorrhagic Brain Injury via Modulation of Blood-Brain Barrier Integrity
por: Xing, Gebeili, et al.
Publicado: (2020)

Brain transforms natural killer cells that exacerbate brain edema after intracerebral hemorrhage
por: Li, Zhiguo, et al.
Publicado: (2020)

Neuroinflammation after intracerebral hemorrhage
por: Mracsko, Eva, et al.
Publicado: (2014)

Microglial pyroptosis: Therapeutic target in secondary brain injury following intracerebral hemorrhage
por: Gu, Lingui, et al.
Publicado: (2022)

Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage
por: Li, Minshu, et al.
Publicado: (2016)

Selective NLRP3 (Pyrin Domain–Containing Protein 3) Inflammasome Inhibitor Reduces Brain Injury After Intracerebral Hemorrhage
por: Ren, Honglei, et al.
Publicado: (2018)

Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage
por: Cai, Jia-Chen, et al.
Publicado: (2018)

Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage
por: Taylor, Roslyn A., et al.
Publicado: (2013)

Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets
por: Tschoe, Christine, et al.
Publicado: (2020)

Dysregulation of microRNA and Intracerebral Hemorrhage: Roles in Neuroinflammation
por: Kashif, Hisham, et al.
Publicado: (2021)

Inhibition of activator protein 1 attenuates neuroinflammation and brain injury after experimental intracerebral hemorrhage
por: Wei, Chang‐Juan, et al.
Publicado: (2019)

The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats
por: Gan, Hui, et al.
Publicado: (2021)

Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner
por: Wu, Yang, et al.
Publicado: (2023)

Neuroinflammation of microglia polarization in intracerebral hemorrhage and its potential targets for intervention
por: Yang, Guoqiang, et al.
Publicado: (2022)

Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice
por: Yu, Xiaobo, et al.
Publicado: (2021)

Neuroprotection by Nrf2 via modulating microglial phenotype and phagocytosis after intracerebral hemorrhage
por: Liang, Chuntian, et al.
Publicado: (2023)

Spatiotemporal Cofilin Signaling, Microglial Activation, Neuroinflammation, and Cognitive Impairment Following Hemorrhagic Brain Injury
por: Almarghalani, Daniyah A., et al.
Publicado: (2023)

Hypoxia-preconditioned mesenchymal stem cells attenuate microglial pyroptosis after intracerebral hemorrhage
por: Liu, Jianyang, et al.
Publicado: (2021)

Over-Activated Proteasome Mediates Neuroinflammation on Acute Intracerebral Hemorrhage in Rats
por: Liew, Hock-Kean, et al.
Publicado: (2019)

Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage
por: Zi, Liu, et al.
Publicado: (2021)

Atorvastatin combined with low-dose dexamethasone improves the neuroinflammation and survival in mice with intracerebral hemorrhage
por: Song, Yiming, et al.
Publicado: (2022)

Perampanel, an AMPAR antagonist, alleviates experimental intracerebral hemorrhage-induced brain injury via necroptosis and neuroinflammation
por: Yang, Lixiang, et al.
Publicado: (2021)

Organ- and cell-specific immune responses are associated with the outcomes of intracerebral hemorrhage
por: Zhang, Jing, et al.
Publicado: (2018)

Fate of Diffusion Restricted Lesions in Acute Intracerebral Hemorrhage
por: Tsai, Yuan-Hsiung, et al.
Publicado: (2014)

Glibenclamide Attenuates Neuroinflammation and Promotes Neurological Recovery After Intracerebral Hemorrhage in Aged Rats
por: Jiang, Bing, et al.
Publicado: (2021)

Simvastatin Upregulates Lipoxin A4 and Accelerates Neuroinflammation Resolution After Intracerebral Hemorrhage
por: Zhang, Jianbo, et al.
Publicado: (2022)

Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice
por: Fang, Yongkang, et al.
Publicado: (2019)

Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats
por: Liew, Hock-Kean, et al.
Publicado: (2012)

MicroRNAs modulate neuroinflammation after intracerebral hemorrhage: Prospects for new therapy
por: Xia, Siqi, et al.
Publicado: (2022)

Berberine mitigates intracerebral hemorrhage-induced neuroinflammation in a gut microbiota-dependent manner in mice
por: Liu, Jing, et al.
Publicado: (2023)

Glymphatic Drainage Blocking Aggravates Brain Edema, Neuroinflammation via Modulating TNF-α, IL-10, and AQP4 After Intracerebral Hemorrhage in Rats
por: Liu, Xichang, et al.
Publicado: (2021)

Baicalin Attenuates Brain Edema in a Rat Model of Intracerebral Hemorrhage
por: Zhou, Qing-Bo, et al.
Publicado: (2013)

Modes of Brain Cell Death Following Intracerebral Hemorrhage
por: Zhang, Yan, et al.
Publicado: (2022)

Inflammatory Regulation by Driving Microglial M2 Polarization: Neuroprotective Effects of Cannabinoid Receptor-2 Activation in Intracerebral Hemorrhage
por: Lin, Li, et al.
Publicado: (2017)

Comparison of humoral neuroinflammation and adhesion molecule expression in two models of experimental intracerebral hemorrhage
por: Liesz, Arthur, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_lgo9a3t9jjpqi9hdiru74tjf3g