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RNAseq reveals extensive metabolic disruptions in the sensitive SF-295 cell line treated with schweinfurthins

The schweinfurthin family of natural compounds exhibit a unique and potent differential cytotoxicity against a number of cancer cell lines and may reduce tumor growth in vivo. In some cell lines, such as SF-295 glioma cells, schweinfurthins elicit cytotoxicity at nanomolar concentrations. However, o...

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Detalles Bibliográficos
Autores principales: Weissenrieder, J. S., Weissenkampen, J. D., Reed, J. L., Green, M. V., Zheng, C., Neighbors, J. D., Liu, D. J., Hohl, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748991/
https://www.ncbi.nlm.nih.gov/pubmed/35013404
http://dx.doi.org/10.1038/s41598-021-04117-7