Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson’s disease

Parkinson’s disease is a neurodegenerative disease characterized by the formation of neuronal inclusions of α-synuclein in patient brains. As the disease progresses, toxic α-synuclein aggregates transmit throughout the nervous system. No effective disease-modifying therapy has been established, and...

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Detalles Bibliográficos
Autores principales: Hideshima, Makoto, Kimura, Yasuyoshi, Aguirre, César, Kakuda, Keita, Takeuchi, Toshihide, Choong, Chi-Jing, Doi, Junko, Nabekura, Kei, Yamaguchi, Keiichi, Nakajima, Kichitaro, Baba, Kousuke, Nagano, Seiichi, Goto, Yuji, Nagai, Yoshitaka, Mochizuki, Hideki, Ikenaka, Kensuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748996/
https://www.ncbi.nlm.nih.gov/pubmed/35013421
http://dx.doi.org/10.1038/s41598-021-04131-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748996/
https://www.ncbi.nlm.nih.gov/pubmed/35013421
http://dx.doi.org/10.1038/s41598-021-04131-9

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