The downregulation of type I IFN signaling in G-MDSCs under tumor conditions promotes their development towards an immunosuppressive phenotype

Tumors modify myeloid cell differentiation and induce an immunosuppressive microenvironment. Granulocytic myeloid-derived suppressor cells (G-MDSCs), the main subgroup of myeloid-derived suppressor cells (MDSCs), are immature myeloid cells (IMCs) with immunosuppressive activity and exist in tumor-be...

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Detalles Bibliográficos
Autores principales: Sun, Yingying, Han, Xiaoqing, Shang, Chao, Wang, Yawei, Xu, Boya, Jiang, Shu, Mo, Yan, Wang, Dake, Ke, Yueshuang, Zeng, Xianlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748997/
https://www.ncbi.nlm.nih.gov/pubmed/35013108
http://dx.doi.org/10.1038/s41419-021-04487-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8748997/
https://www.ncbi.nlm.nih.gov/pubmed/35013108
http://dx.doi.org/10.1038/s41419-021-04487-w

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