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Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells
PURPOSE: Sphingosine kinase is a lipid kinase that phosphorylates sphingosine to generate sphingosine 1-phosphate (S1P). S1P regulates pancreatic islet β-cell endoplasmic reticulum stress and proliferation. Type 1 and type 2 diabetes share some key pathogenic processes. In this study, we investigate...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Pediatric Endocrinology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749023/ https://www.ncbi.nlm.nih.gov/pubmed/34015900 http://dx.doi.org/10.6065/apem.2040266.133 |