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Identification of sphingosine 1-phosphate level and MAPK/ERK signaling in pancreatic β cells

PURPOSE: Sphingosine kinase is a lipid kinase that phosphorylates sphingosine to generate sphingosine 1-phosphate (S1P). S1P regulates pancreatic islet β-cell endoplasmic reticulum stress and proliferation. Type 1 and type 2 diabetes share some key pathogenic processes. In this study, we investigate...

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Detalles Bibliográficos
Autores principales: Park, Ji Hyun, Park, Kwan Kyu, Choe, Jae Young, Jang, Kyung Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Pediatric Endocrinology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749023/
https://www.ncbi.nlm.nih.gov/pubmed/34015900
http://dx.doi.org/10.6065/apem.2040266.133