Statins mediate anti- and pro-tumourigenic functions by remodelling the tumour microenvironment

Anti-cancer properties of statins are controversial and possibly context dependent. Recent pathology/epidemiology studies of human lung adenocarcinoma showed reduced pro-tumourigenic macrophages associated with a shift to lower-grade tumours amongst statin users but, paradoxically, worse survival co...

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Detalles Bibliográficos
Autores principales: Kamata, Tamihiro, Al Dujaily, Esraa, Alhamad, Salwa, So, Tsz Y., Margaritaki, Olga, Giblett, Susan, Pringle, J. Howard, Le Quesne, John, Pritchard, Catrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749029/
https://www.ncbi.nlm.nih.gov/pubmed/34779486
http://dx.doi.org/10.1242/dmm.049148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749029/
https://www.ncbi.nlm.nih.gov/pubmed/34779486
http://dx.doi.org/10.1242/dmm.049148

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