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Dimethyl Fumarate as the Peripheral Blood Inflammatory Mediators Inhibitor in Prevention of Streptozotocin-Induced Neuroinflammation in Aged Rats

PURPOSE: Intracerebroventricular-(ICV)-streptozotocin-(STZ)-induced neuroinflammation is a model of Alzheimer’s disease (AD) compatible with the inflammation hypothesis of ageing (“inflammaging” state). Previously, we observed age-dependent (young vs aged) dimethyl fumarate (DMF)-induced anti-inflam...

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Detalles Bibliográficos
Autores principales: Wrona, Danuta, Majkutewicz, Irena, Świątek, Grzegorz, Dunacka, Joanna, Grembecka, Beata, Glac, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749052/
https://www.ncbi.nlm.nih.gov/pubmed/35027835
http://dx.doi.org/10.2147/JIR.S342280