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Mutational widening of constrictions in a formate–nitrite/H(+) transporter enables aquaporin-like water permeability and proton conductance
The unrelated protein families of the microbial formate–nitrite transporters (FNTs) and aquaporins (AQP) likely adapted the same protein fold through convergent evolution. FNTs facilitate weak acid anion/H(+) cotransport, whereas AQP water channels strictly exclude charged substrates including proto...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749060/ https://www.ncbi.nlm.nih.gov/pubmed/34929166 http://dx.doi.org/10.1016/j.jbc.2021.101513 |