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Mutational widening of constrictions in a formate–nitrite/H(+) transporter enables aquaporin-like water permeability and proton conductance

The unrelated protein families of the microbial formate–nitrite transporters (FNTs) and aquaporins (AQP) likely adapted the same protein fold through convergent evolution. FNTs facilitate weak acid anion/H(+) cotransport, whereas AQP water channels strictly exclude charged substrates including proto...

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Detalles Bibliográficos
Autores principales: Schmidt, Jana D.R., Beitz, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749060/
https://www.ncbi.nlm.nih.gov/pubmed/34929166
http://dx.doi.org/10.1016/j.jbc.2021.101513

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