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Use of orthogonal serine integrases to multiplex plasmid conjugation and integration from E. coli into Streptomyces

Some major producers of useful bioactive natural products belong to the genus Streptomyces or related actinobacteria. Genetic engineering of these bacteria and the pathways that synthesize their valuable products often relies on serine integrases. To further improve the flexibility and efficiency of...

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Detalles Bibliográficos
Autores principales: Gao, Hong, Smith, Margaret C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749152/
https://www.ncbi.nlm.nih.gov/pubmed/35024553
http://dx.doi.org/10.1099/acmi.0.000291