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Use of orthogonal serine integrases to multiplex plasmid conjugation and integration from E. coli into Streptomyces
Some major producers of useful bioactive natural products belong to the genus Streptomyces or related actinobacteria. Genetic engineering of these bacteria and the pathways that synthesize their valuable products often relies on serine integrases. To further improve the flexibility and efficiency of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Microbiology Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749152/ https://www.ncbi.nlm.nih.gov/pubmed/35024553 http://dx.doi.org/10.1099/acmi.0.000291 |