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Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment

OBJECTIVE: Growth differentiation factor 15 (GDF15) is known to play a role in feeding, nausea, and body weight, with action through the GFRAL-RET receptor complex in the area postrema (AP) and nucleus tractus solitarius (NTS). To further elucidate the underlying cell type-specific molecular mechani...

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Detalles Bibliográficos
Autores principales: Reiner, Benjamin C., Crist, Richard C., Borner, Tito, Doyle, Robert P., Hayes, Matthew R., De Jonghe, Bart C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749158/
https://www.ncbi.nlm.nih.gov/pubmed/34942400
http://dx.doi.org/10.1016/j.molmet.2021.101422