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Single nuclei RNA sequencing of the rat AP and NTS following GDF15 treatment
OBJECTIVE: Growth differentiation factor 15 (GDF15) is known to play a role in feeding, nausea, and body weight, with action through the GFRAL-RET receptor complex in the area postrema (AP) and nucleus tractus solitarius (NTS). To further elucidate the underlying cell type-specific molecular mechani...
Autores principales: | Reiner, Benjamin C., Crist, Richard C., Borner, Tito, Doyle, Robert P., Hayes, Matthew R., De Jonghe, Bart C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749158/ https://www.ncbi.nlm.nih.gov/pubmed/34942400 http://dx.doi.org/10.1016/j.molmet.2021.101422 |
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