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SNF5, a core subunit of SWI/SNF complex, regulates melanoma cancer cell growth, metastasis, and immune escape in response to matrix stiffness

Increased stiffness of the extracellular matrix is an important hallmark of melanoma development and progression, but its regulatory role and related mechanisms remain unclear. We adapted polydimethylsiloxane (PDMS)-micropillar-based matrix platform and investigated the effect of matrix stiffness on...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Zhao, Meilian, Zhang, Lu, Shen, Dongliang, Xu, Xichao, Yi, Qian, Tang, Liling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749166/
https://www.ncbi.nlm.nih.gov/pubmed/34999540
http://dx.doi.org/10.1016/j.tranon.2021.101335