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Apolipoprotein E derived from CD11c(+) cells ameliorates atherosclerosis

Atherosclerosis is studied in models with dysfunctional lipid homeostasis—predominantly the ApoE(−/−) mouse. The role of antigen-presenting cells (APCs) for lipid homeostasis is not clear. Using a LacZ reporter mouse, we showed that CD11c(+) cells were enriched in aortae of ApoE(−/−) mice. Systemic...

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Detalles Bibliográficos
Autores principales: Sauter, Manuela, Sauter, Reinhard J., Nording, Henry, Lin, Chaolan, Olbrich, Marcus, Autenrieth, Stella, Gleissner, Christian, Thunemann, Martin, Otero, Nadia, Lutgens, Esther, Aherrahrou, Zouhair, Wolf, Dennis, Zender, Lars, Meuth, Sven, Feil, Robert, Langer, Harald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749187/
https://www.ncbi.nlm.nih.gov/pubmed/35036868
http://dx.doi.org/10.1016/j.isci.2021.103677