Galactose-decorated liver tumor-specific nanoliposomes incorporating selective BRD4-targeted PROTAC for hepatocellular carcinoma therapy

This research deals with the development of asialoglycoprotein receptors (ASGPR) directed nanoliposomes incorporating a novel BRD4 (Bromodomain-containing protein 4) protein-targeted PROTAC (Proteolysis Targeting Chimera), ARV-825 (ARV) (GALARV), and to investigate the anticancer efficacy of GALARV...

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Detalles Bibliográficos
Autores principales: Saraswat, Aishwarya, Vemana, Hari Priya, Dukhande, Vikas V., Patel, Ketan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749201/
https://www.ncbi.nlm.nih.gov/pubmed/35036599
http://dx.doi.org/10.1016/j.heliyon.2021.e08702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749201/
https://www.ncbi.nlm.nih.gov/pubmed/35036599
http://dx.doi.org/10.1016/j.heliyon.2021.e08702

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