Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation

Abnormal activation of SETBP1 due to overexpression or missense mutations occurs frequently in various myeloid neoplasms and associates with poor prognosis. Direct activation of Hoxa9/Hoxa10/Myb transcription by SETBP1 and its missense mutants is essential for their transforming capability; however,...

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Detalles Bibliográficos
Autores principales: Nguyen, Nhu, Gudmundsson, Kristbjorn O., Soltis, Anthony R., Oakley, Kevin, Roy, Kartik R., Han, Yufen, Gurnari, Carmelo, Maciejewski, Jaroslaw P., Crouch, Gary, Ernst, Patricia, Dalgard, Clifton L., Du, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749219/
https://www.ncbi.nlm.nih.gov/pubmed/35036869
http://dx.doi.org/10.1016/j.isci.2021.103679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749219/
https://www.ncbi.nlm.nih.gov/pubmed/35036869
http://dx.doi.org/10.1016/j.isci.2021.103679

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