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Molecular structure of an amyloid fibril formed by FUS low-complexity domain

FUS is a multifunctional nuclear protein which undergoes liquid–liquid phase separation in response to stress and DNA damage. Dysregulation of FUS dynamic phase separation leads to formation of pathological fibril closely associated with neurodegenerative diseases such as amyotrophic lateral scleros...

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Detalles Bibliográficos
Autores principales: Sun, Yunpeng, Zhang, Shenqing, Hu, Jiaojiao, Tao, Youqi, Xia, Wencheng, Gu, Jinge, Li, Yichen, Cao, Qin, Li, Dan, Liu, Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749265/
https://www.ncbi.nlm.nih.gov/pubmed/35036880
http://dx.doi.org/10.1016/j.isci.2021.103701