Genomic and Phenotypic Characterization of Experimentally Selected Resistant Leishmania donovani Reveals a Role for Dynamin-1-Like Protein in the Mechanism of Resistance to a Novel Antileishmanial Compound

The implementation of prospective drug resistance (DR) studies in the research-and-development (R&D) pipeline is a common practice for many infectious diseases but not for neglected tropical diseases (NTDs). Here, we explored and demonstrated the importance of this approach using as paradigms Le...

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Detalles Bibliográficos
Autores principales: Hefnawy, Aya, Negreira, Gabriel, Jara, Marlene, Cotton, James A., Maes, Ilse, D’Haenens, Erika, Imamura, Hideo, Cuypers, Bart, Monsieurs, Pieter, Mouchtoglou, Christina, De Winter, Hans, Pintelon, Isabel, Timmermans, Jean-Pierre, Berriman, Matt, Sanders, Mandy, Martin, Julio, de Muylder, Geraldine, Dujardin, Jean-Claude, Sterckx, Yann G.-J., Domagalska, Malgorzata Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749414/
https://www.ncbi.nlm.nih.gov/pubmed/35012338
http://dx.doi.org/10.1128/mbio.03264-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749414/
https://www.ncbi.nlm.nih.gov/pubmed/35012338
http://dx.doi.org/10.1128/mbio.03264-21

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