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Elevated Levels of an Enzyme Involved in Coenzyme B(12) Biosynthesis Kills Escherichia coli

Cobamides are cobalt-containing cyclic tetrapyrroles involved in the metabolism of organisms from all domains of life but produced de novo only by some bacteria and archaea. The pathway is thought to involve up to 30 enzymes, five of which comprise the so-called “late” steps of cobamide biosynthesis...

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Detalles Bibliográficos
Autores principales: Jeter, Victoria L., Escalante-Semerena, Jorge C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749415/
https://www.ncbi.nlm.nih.gov/pubmed/35012330
http://dx.doi.org/10.1128/mbio.02697-21