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Immunoprotection against Cryptococcosis Offered by Znf2 Depends on Capsule and the Hyphal Morphology

Systemic cryptococcosis is fatal without treatment. Globally, this disease kills 180,000 of the 225,000 infected people each year, even with the use of antifungal therapies. Currently, there is no vaccine to prevent cryptococcosis. Previously, we discovered that Znf2, a morphogenesis regulator that...

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Detalles Bibliográficos
Autores principales: Lin, Jianfeng, Pham, Tuyetnhu, Hipsher, Kenton, Glueck, Nathan, Fan, Yumeng, Lin, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749420/
https://www.ncbi.nlm.nih.gov/pubmed/35012334
http://dx.doi.org/10.1128/mbio.02785-21