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Molecular Insights into the Assembly and Functional Diversification of Typhoid Toxin

Typhoid toxin is an A(2)B(5) protein toxin and an important virulence factor for the human-adapted bacterial pathogen Salmonella enterica serovar Typhi, the causative agent of typhoid fever. Typhoid toxin contains two enzymatic subunits, PltA and CdtB, which dock onto a pentameric delivery platform...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoyu, Chen, Zhe, Jiao, Xuyao, Jiang, Xukai, Qiu, Jicheng, You, Fuping, Long, Hongan, Cao, Hongzhi, Fowler, Casey C., Gao, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749428/
https://www.ncbi.nlm.nih.gov/pubmed/35012347
http://dx.doi.org/10.1128/mbio.01916-21