Inhibition of O‐GlcNAcylation protects from Shiga toxin‐mediated cell injury and lethality in host

Shiga toxins (Stxs) produced by enterohemorrhagic Escherichia coli (EHEC) are the major virulence factors responsible for hemorrhagic colitis, which can lead to life‐threatening systemic complications including acute renal failure (hemolytic uremic syndrome) and neuropathy. Here, we report that O‐Gl...

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Detalles Bibliográficos
Autores principales: Lee, Kyung‐Soo, Lee, Jieun, Lee, Pureum, Jeon, Bong Chan, Song, Min Yeong, Kwak, Sojung, Lee, Jungwoon, Kim, Jun‐Seob, Kim, Doo‐Jin, Kim, Ji Hyung, Tesh, Vernon L, Lee, Moo‐Seung, Park, Sung‐Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749473/
https://www.ncbi.nlm.nih.gov/pubmed/34842355
http://dx.doi.org/10.15252/emmm.202114678

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749473/
https://www.ncbi.nlm.nih.gov/pubmed/34842355
http://dx.doi.org/10.15252/emmm.202114678

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