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BRCA1 and Metastasis: Outcome of Defective DNA Repair

SIMPLE SUMMARY: BRCA1 has critical functions in accurately repairing double stand breaks in the DNA through a process known as homologous recombination. BRCA1 also has various functions in other cellular processes that safeguard the genome. Thus, mutations or silencing of this tumor suppressor signi...

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Detalles Bibliográficos
Autores principales: Krishnan, Rehna, Patel, Parasvi S., Hakem, Razqallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8749860/
https://www.ncbi.nlm.nih.gov/pubmed/35008272
http://dx.doi.org/10.3390/cancers14010108