Oxidative Damage Induced by Phototoxic Pheophorbide a 17-Diethylene Glycol Ester Encapsulated in PLGA Nanoparticles

Pheophorbide a 17-diethylene glycol ester (XL-8), is a promising high-active derivative of known photosensitizer chlorin e6 used in photodynamic therapy. However, high lipophilicity and poor tumor accumulation limit XL-8 therapeutic application. We developed a novel XL-8 loaded with poly(D,L-lactide...

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Detalles Bibliográficos
Autores principales: Mollaeva, Mariia R., Nikolskaya, Elena, Beganovskaya, Veronika, Sokol, Maria, Chirkina, Margarita, Obydennyi, Sergey, Belykh, Dmitry, Startseva, Olga, Mollaev, Murad D., Yabbarov, Nikita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750000/
https://www.ncbi.nlm.nih.gov/pubmed/34943088
http://dx.doi.org/10.3390/antiox10121985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750000/
https://www.ncbi.nlm.nih.gov/pubmed/34943088
http://dx.doi.org/10.3390/antiox10121985

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