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Bak and Bcl-xL Participate in Regulating Sensitivity of Solid Tumor Derived Cell Lines to Mcl-1 Inhibitors

SIMPLE SUMMARY: Apoptosis is one of the best-known types of programmed cell death. This process is regulated by a number of genes and proteins, among which the Bcl-2 protein family plays a key role. This family includes anti- and proapoptotic proteins. Cancer cell resistance to apoptosis is commonly...

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Detalles Bibliográficos
Autores principales: Senichkin, Viacheslav V., Pervushin, Nikolay V., Zamaraev, Alexey V., Sazonova, Elena V., Zuev, Anton P., Streletskaia, Alena Y., Prikazchikova, Tatiana A., Zatsepin, Timofei S., Kovaleva, Olga V., Tchevkina, Elena M., Zhivotovsky, Boris, Kopeina, Gelina S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750033/
https://www.ncbi.nlm.nih.gov/pubmed/35008345
http://dx.doi.org/10.3390/cancers14010181