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Correlation Analysis of Protein Expression of 10 HDAC/Sirtuin Isoenzymes with Sensitivities of 23 Anticancer Drugs in 17 Cancer Cell Lines and Potentiation of Drug Activity by Co-Treatment with HDAC Inhibitors

SIMPLE SUMMARY: Protein expression profiles of 10 HDAC/Sirtuin isoenzymes in two panels of human cancer cell lines were compared with each other and with the potencies of various anticancer drugs by Pearson and Spearman correlation analysis to identify patterns of enzyme expression and anticancer ac...

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Detalles Bibliográficos
Autores principales: Behnisch-Cornwell, Steven, Grathwol, Christoph W., Schulig, Lukas, Voigt, Anika, Baecker, Daniel, Link, Andreas, Bednarski, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750037/
https://www.ncbi.nlm.nih.gov/pubmed/35008351
http://dx.doi.org/10.3390/cancers14010187