Lack of Endothelial α1AMPK Reverses the Vascular Protective Effects of Exercise by Causing eNOS Uncoupling

Voluntary exercise training is an effective way to prevent cardiovascular disease, since it results in increased NO bioavailability and decreased reactive oxygen species (ROS) production. AMP-activated protein kinase (AMPK), especially its α1AMPK subunit, modulates ROS-dependent vascular homeostasis...

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Detalles Bibliográficos
Autores principales: Jansen, Thomas, Kvandová, Miroslava, Schmal, Isabella, Kalinovic, Sanela, Stamm, Paul, Kuntic, Marin, Foretz, Marc, Viollet, Benoit, Daiber, Andreas, Oelze, Matthias, Keaney, John F., Münzel, Thomas, Schulz, Eberhard, Kröller-Schön, Swenja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750041/
https://www.ncbi.nlm.nih.gov/pubmed/34943078
http://dx.doi.org/10.3390/antiox10121974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750041/
https://www.ncbi.nlm.nih.gov/pubmed/34943078
http://dx.doi.org/10.3390/antiox10121974

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